Effects of tartrazine on growth and brain biochemistry of Indian major carps on long-term exposure

Background: Synthetic azo dyes are very extensively using various industries such as food items and non-food items. Tartrazine is well known dye due to its wide range of applications, also acid yellow 23. Most release these containing effluents into water bodies without proper treatment. There no well-documented study about the toxicological effect tartrazine in fishes. studies with concentrated humans rats. However, there a high chance reaching natural either through direct or indirect deposition necessity understanding effects on fish.Objective: The was conducted assess synthetic fishes long-term exposure. Materials Methods: Labeo rohita commonly Indian major carp selected experimental fish parameters discussed growth terms condition factors biochemical changes brain. Experimental were grouped after acclimatization seven days control (C), test 1 (T1), (T3). analyzed include total proteins, carbohydrates, lipids, free amino acids; antiperoxidative enzymes- GST, GR, GPx, SOD, CAT; lipid peroxidation product MDA activity AChE. After chronic exposure experiment 75 days, subjected morphometric measurements analysis. Results: results show that weight reduced significantly (P